Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AIA76088.1Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)    
Predicted Functional Partners:
AIA76090.1
Restriction endonuclease, type I, EcoRI, R subunit/Type III; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.842
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
  
 
 0.749
AIA76086.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.731
AIA76089.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.691
AIA76085.1
Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.463
AIA76087.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.463
AIA76091.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.460
AIA76092.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.460
AIA75159.1
DNA methylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.423
mutM
5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
  
  
 0.409
Your Current Organism:
Halomonas campaniensis
NCBI taxonomy Id: 213554
Other names: ATCC BAA-966, DSM 15293, H. campaniensis, Halomonas campaniae, Halomonas campaniensis Romano et al. 2005, Halomonas campisalis subsp. campaniae, strain 5AG
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