Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AIA76642.1Cation transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)    
Predicted Functional Partners:
leuA-2
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
     
 0.773
AIA76643.1
Subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved with K+; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.653
AIA76645.1
Cation:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.652
AIA76646.1
Cation:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.640
AIA76644.1
NADH-ubiquinone oxidoreductase subunit 4L; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.633
AIA76647.1
Cation:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.633
AIA76648.1
Sodium:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.562
AIA76650.1
Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.496
AIA75471.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.443
parC
DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
       0.428
Your Current Organism:
Halomonas campaniensis
NCBI taxonomy Id: 213554
Other names: ATCC BAA-966, DSM 15293, H. campaniensis, Halomonas campaniae, Halomonas campaniensis Romano et al. 2005, Halomonas campisalis subsp. campaniae, strain 5AG
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.