Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKB63221.1Fe-S oxidoreductase; Homology to heterodisulfide reductase 2 iron-sulfur subunit. (387 aa)    
Predicted Functional Partners:
AKB63220.1
FAD/FMN-containing dehydrogenase.
 
 0.996
AKB64817.1
Fumarate hydratase class I, aerobic; L(+)-tartrate dehydratase beta subunit.
 
  
 0.967
AKB64818.1
Fumarate hydratase class I, aerobic; L(+)-tartrate dehydratase alpha subunit.
    
 0.957
AKB64580.1
PUA-PAPS reductase like fusion.
 
 
 0.814
AKB63218.1
Ribosomal-protein-S18p-alanine acetyltransferase.
       0.723
AKB63219.1
Archaeosine tRNA-ribosyltransferase type 2.
       0.707
AKB64110.1
CoB--CoM heterodisulfide reductase subunit C.
 
 
 0.611
AKB64111.1
CoB--CoM heterodisulfide reductase subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
 
  
 0.574
AKB63516.1
CoB--CoM heterodisulfide reductase subunit C.
 
 
 0.571
AKB64109.1
CoB--CoM heterodisulfide reductase subunit B.
 
 
 0.568
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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