Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB63402.1Iron-sulfur-binding protein. (177 aa)    
Predicted Functional Partners:
AKB63403.1
Putative transcriptional regulator.
       0.893
AKB64552.1
Iron-sulfur cluster binding protein.
  
 
 0.830
AKB65412.1
Hypothetical protein.
  
 
 0.592
AKB65572.1
Energy-conserving hydrogenase (ferredoxin), subunit F.
  
 
 0.592
AKB64135.1
Hypothetical protein.
 
  
 0.538
AKB64339.1
Hypothetical protein.
 
  
 0.538
AKB65601.1
Cell surface protein.
 
  
 0.528
AKB64012.1
Ferredoxin.
  
 
 0.509
AKB64013.1
Ferredoxin.
  
 
 0.509
AKB64704.1
Ketoisovalerate oxidoreductase subunit VorC.
  
 
 0.509
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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