STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB63432.1Hydrogenase, group 4, HycE subunit, putative. (541 aa)    
Predicted Functional Partners:
AKB63431.1
Hydrogenase, group 4, HycG subunit, putative.
 
 0.999
AKB63433.1
Hydrogenase-4 component F.
 
 0.999
AKB63435.1
Formate hydrogenlyase subunit 4.
 
 0.999
AKB63436.1
Hydrogenase, HycC subunit, putative.
 
 0.999
AKB65412.1
Hypothetical protein.
 
 0.999
AKB65572.1
Energy-conserving hydrogenase (ferredoxin), subunit F.
 
 0.999
AKB65409.1
NADH-quinone oxidoreductase subunit C/D.
 
 0.998
AKB65410.1
NADH-quinone oxidoreductase subunit C/D.
 
0.998
fpoH
FPO subunit H; FPO shuttles electrons from F(420)H(2), via FAD and iron- sulfur (Fe-S) centers, to quinones in the F(420)H(2):heterodisulfide oxidoreduction chain. The immediate electron acceptor for the enzyme in this species is believed to be methanophenazine. Couples the redox reaction to proton translocation (for every two electrons transferred, 0.9 hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
 
 0.998
AKB65575.1
Energy-conserving hydrogenase (ferredoxin), subunit C.
 
 0.998
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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