STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ilvEBranched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (292 aa)    
Predicted Functional Partners:
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.999
AKB64702.1
Ketoisovalerate oxidoreductase subunit VorA.
    
 0.979
AKB63228.1
2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 0.971
AKB66520.1
Pyruvate:ferredoxin oxidoreductase, beta subunit.
    
 0.952
AKB64703.1
Ketoisovalerate oxidoreductase subunit VorB.
  
 
 0.947
AKB65190.1
Homoserine dehydrogenase.
 
 
 0.943
AKB64704.1
Ketoisovalerate oxidoreductase subunit VorC.
    
  0.925
AKB66517.1
Pyruvate:ferredoxin oxidoreductase, gamma subunit.
    
 0.911
trpE
Anthranilate synthase, aminase component; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high c [...]
  
 
 0.897
AKB66519.1
Pyruvate:ferredoxin oxidoreductase, alpha subunit.
  
 
 0.895
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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