STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB63552.1Sensory transduction histidine kinase. (363 aa)    
Predicted Functional Partners:
AKB63429.1
Two-component response regulator.
 
     0.973
AKB64870.1
Response regulator receiver.
 
     0.972
AKB65033.1
Response regulator receiver.
 
     0.965
AKB66534.1
Chemotaxis protein methyltransferase CheR.
 
      0.848
AKB64172.1
Chemotaxis protein methyltransferase CheR.
 
      0.787
AKB64678.1
Response regulator receiver.
 
     0.787
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
      
 0.751
AKB66530.1
Two-component response regulator.
  
     0.714
AKB65544.1
Phosphate regulon transcriptional regulatory protein PhoB (SphR).
  
     0.643
AKB64344.1
Sensory transduction histidine kinase.
 
     0.607
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.