eif5a protein (Methanosarcina mazei) - STRING interaction network

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eif5a

Eukaryotic translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (128 aa)

Predicted Functional Partners:

rpl2

0.999

rpl13

0.991

rps12

0.990

rps6e

0.989

rpl18

0.989

rps19e

0.988

rpl14

0.988

rpl21e

0.987

rps4e

0.987

rps17

0.987

Your Current Organism:

Methanosarcina mazei

NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
eif5a	rpl13	MSMAS_0383	MSMAS_2922	Eukaryotic translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.	LSU ribosomal protein L13Ae (L13p); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.991
eif5a	rpl14	MSMAS_0383	MSMAS_2550	Eukaryotic translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.	LSU ribosomal protein L23e (L14p); Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	0.988
eif5a	rpl18	MSMAS_0383	MSMAS_2541	Eukaryotic translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.	LSU ribosomal protein L5e (L18p); This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.	0.989
eif5a	rpl2	MSMAS_0383	MSMAS_2557	Eukaryotic translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.	LSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	0.999
eif5a	rpl21e	MSMAS_0383	MSMAS_2168	Eukaryotic translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.	LSU ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.	0.987
eif5a	rps12	MSMAS_0383	MSMAS_2428	Eukaryotic translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.	SSU ribosomal protein S23e (S12p); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.	0.990
eif5a	rps17	MSMAS_0383	MSMAS_2551	Eukaryotic translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.	SSU ribosomal protein S11e (S17p); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.	0.987
eif5a	rps19e	MSMAS_0383	MSMAS_0503	Eukaryotic translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.	SSU ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.	0.988
eif5a	rps4e	MSMAS_0383	MSMAS_2548	Eukaryotic translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.	SSU ribosomal protein S4e; Belongs to the eukaryotic ribosomal protein eS4 family.	0.987
eif5a	rps6e	MSMAS_0383	MSMAS_2239	Eukaryotic translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.	SSU ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.	0.989
rpl13	eif5a	MSMAS_2922	MSMAS_0383	LSU ribosomal protein L13Ae (L13p); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	Eukaryotic translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.	0.991
rpl13	rpl14	MSMAS_2922	MSMAS_2550	LSU ribosomal protein L13Ae (L13p); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	LSU ribosomal protein L23e (L14p); Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	0.996
rpl13	rpl18	MSMAS_2922	MSMAS_2541	LSU ribosomal protein L13Ae (L13p); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	LSU ribosomal protein L5e (L18p); This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.	0.998
rpl13	rpl2	MSMAS_2922	MSMAS_2557	LSU ribosomal protein L13Ae (L13p); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	LSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	0.999
rpl13	rpl21e	MSMAS_2922	MSMAS_2168	LSU ribosomal protein L13Ae (L13p); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	LSU ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.	0.996
rpl13	rps12	MSMAS_2922	MSMAS_2428	LSU ribosomal protein L13Ae (L13p); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	SSU ribosomal protein S23e (S12p); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.	0.994
rpl13	rps17	MSMAS_2922	MSMAS_2551	LSU ribosomal protein L13Ae (L13p); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	SSU ribosomal protein S11e (S17p); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.	0.994
rpl13	rps19e	MSMAS_2922	MSMAS_0503	LSU ribosomal protein L13Ae (L13p); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	SSU ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.	0.993
rpl13	rps4e	MSMAS_2922	MSMAS_2548	LSU ribosomal protein L13Ae (L13p); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	SSU ribosomal protein S4e; Belongs to the eukaryotic ribosomal protein eS4 family.	0.988
rpl13	rps6e	MSMAS_2922	MSMAS_2239	LSU ribosomal protein L13Ae (L13p); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	SSU ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.	0.991