STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB63628.1RecB family exonuclease. (272 aa)    
Predicted Functional Partners:
AKB63629.1
Hypothetical protein.
       0.825
cas2
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
   
 
 0.778
AKB63630.1
Hydroxymethylglutaryl-CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family.
       0.763
AKB63631.1
Beta-ketoacyl synthase/thiolase.
       0.755
AKB63632.1
Conserved protein associated with acetyl-CoA C-acyltransferase.
       0.755
AKB63858.1
Oligosaccharyl transferase.
  
     0.701
AKB63859.1
Oligosaccharyl transferase.
  
     0.700
AKB63633.1
Adenylate cyclase.
       0.695
AKB66458.1
Archaeosortase A.
  
     0.689
AKB66069.1
Hypothetical protein.
  
     0.683
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.