Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB63629.1Hypothetical protein. (246 aa)    
Predicted Functional Partners:
AKB63630.1
Hydroxymethylglutaryl-CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family.
 
    0.989
AKB63632.1
Conserved protein associated with acetyl-CoA C-acyltransferase.
 
    0.961
AKB63631.1
Beta-ketoacyl synthase/thiolase.
  
    0.959
AKB63633.1
Adenylate cyclase.
 
     0.901
AKB63628.1
RecB family exonuclease.
       0.825
AKB65517.1
Conserved transmembrane protein.
 
     0.704
AKB63897.1
His-Xaa-Ser system radical SAM maturase HxsC.
  
     0.699
carS
Phosphatidate cytidylyltransferase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
  
     0.664
AKB63219.1
Archaeosine tRNA-ribosyltransferase type 2.
  
     0.635
AKB63493.1
Hypothetical protein.
  
     0.633
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.