Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKB63630.1Hydroxymethylglutaryl-CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family. (349 aa)    
Predicted Functional Partners:
AKB63631.1
Beta-ketoacyl synthase/thiolase.
 
 0.999
AKB63632.1
Conserved protein associated with acetyl-CoA C-acyltransferase.
 
 
 0.999
AKB64162.1
Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family.
 
 0.999
AKB63629.1
Hypothetical protein.
 
    0.989
AKB66520.1
Pyruvate:ferredoxin oxidoreductase, beta subunit.
    
 0.906
AKB64080.1
2-oxoglutarate oxidoreductase, beta subunit.
    
 0.905
AKB66517.1
Pyruvate:ferredoxin oxidoreductase, gamma subunit.
    
 0.905
AKB66518.1
Pyruvate:ferredoxin oxidoreductase, delta subunit.
    
 0.904
AKB64079.1
2-oxoglutarate oxidoreductase, alpha subunit.
    
  0.901
AKB66519.1
Pyruvate:ferredoxin oxidoreductase, alpha subunit.
    
  0.901
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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