Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB63663.1Hypothetical protein. (720 aa)    
Predicted Functional Partners:
AKB63666.1
Phytoene dehydrogenase.
 
    0.943
AKB65339.1
Ferredoxin.
   
    0.840
AKB65668.1
SAM-dependent methyltransferase.
 
    0.820
AKB63662.1
Dolichol-P-glucose synthetase.
 
  
 0.777
AKB63670.1
Hypothetical protein.
 
     0.774
AKB63247.1
Hypothetical protein.
  
     0.603
cofC
2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family.
  
     0.573
AKB66474.1
Haloacid dehalogenase superfamily protein.
 
     0.506
AKB65930.1
Hypothetical protein.
 
  
 0.503
AKB66370.1
Putative transcriptional regulators.
  
     0.463
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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