STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfdAPrefoldin alpha subunit (GimC alpha subunit); Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. (142 aa)    
Predicted Functional Partners:
pfdB
Prefoldin beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
 
 0.999
rpl18a
LSU ribosomal protein L18Ae.
 
  
 0.869
rpl31e
LSU ribosomal protein L31e; Belongs to the ribosomal protein L31e family.
 
  
 0.850
AKB63401.1
Heat shock protein 60 family chaperone GroEL; Thermosome subunit; Belongs to the TCP-1 chaperonin family.
   
 0.769
AKB66479.1
Heat shock protein 60 family chaperone GroEL; Thermosome subunit; Belongs to the TCP-1 chaperonin family.
   
 0.769
AKB64453.1
Heat shock protein 60 family chaperone GroEL; Thermosome subunit; Belongs to the TCP-1 chaperonin family.
   
 0.760
groL
Heat shock protein 60 family chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 0.760
eif6
Eukaryotic translation initiation factor 6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
 
   
 0.755
AKB63698.1
DNA-binding protein; Belongs to the PDCD5 family.
  
   0.723
ef1b
Translation elongation factor 1 beta subunit; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
  
 
 0.719
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.