STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKB63709.1Geranylfarnesyl diphosphate synthetase; Belongs to the FPP/GGPP synthase family. (285 aa)    
Predicted Functional Partners:
uppS
Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
 
 
 0.986
AKB63708.1
Hypothetical protein.
 
     0.941
AKB66108.1
Geranylfarnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
  
  
0.916
AKB63710.1
Metallo cofactor biosynthesis protein.
       0.865
AKB63414.1
Undecaprenyl diphosphate synthase.
 
 
 0.771
fni
Isopentenyl-diphosphate delta-isomerase, FMN-dependent; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
 
 0.711
rnj
Putative Zn-dependent hydrolase in polyisoprenoid biosynthetic cluster; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
  
    0.686
AKB65409.1
NADH-quinone oxidoreductase subunit C/D.
 
  
 0.650
AKB63630.1
Hydroxymethylglutaryl-CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family.
 
 
 0.632
AKB64505.1
Undecaprenyl diphosphate synthase.
 
 
 0.623
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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