STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB63721.1[NiFe] hydrogenase metallocenter assembly protein HypF. (772 aa)    
Predicted Functional Partners:
AKB65578.1
[NiFe] hydrogenase metallocenter assembly protein HypE.
 
 0.990
AKB65581.1
[NiFe] hydrogenase metallocenter assembly protein HypD.
 
  
 0.914
AKB65584.1
Methanophenazine hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 
 0.772
AKB65715.1
Methanophenazine hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 
 0.771
AKB65709.1
Methanophenazine hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 
 0.769
AKB65582.1
[NiFe] hydrogenase metallocenter assembly protein HypC.
 
 
 0.758
AKB65717.1
[NiFe] hydrogenase metallocenter assembly protein HypC.
 
 
 0.756
hypA
[NiFe] hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
   
 0.730
AKB65710.1
Methanophenazine hydrogenase small subunit precursor.
 
 
 
 0.719
AKB64841.1
Coenzyme F420 hydrogenase subunit alpha.
 
 
 
 0.711
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.