Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB63745.1Type I restriction-modification system, restriction subunit R. (963 aa)    
Predicted Functional Partners:
AKB63747.1
Type I restriction-modification system, DNA-methyltransferase subunit M.
 
  
 0.939
AKB63746.1
Type I restriction-modification system, specificity subunit S.
 
  
 0.929
AKB64896.1
Type I restriction-modification system, DNA-methyltransferase subunit M.
 
  
 0.877
AKB64900.1
Type I restriction-modification system, specificity subunit S.
 
  
 0.854
AKB63748.1
Type I restriction-modification system, DNA-methyltransferase subunit M.
 
  
 0.739
AKB63749.1
EcoKI restriction-modification system protein HsdS.
  
  
 0.659
AKB65693.1
Type I restriction-modification system, specificity subunit S.
 
  
 0.542
AKB64070.1
Type I restriction-modification system, DNA-methyltransferase subunit M.
  
  
 0.476
AKB64732.1
Type I restriction-modification system, DNA-methyltransferase subunit M.
  
  
 0.476
AKB65167.1
Type I restriction-modification system specificity subunit.
  
  
 0.476
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.