Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB64017.1Hypothetical protein. (199 aa)    
Predicted Functional Partners:
AKB66113.1
Hypothetical protein; COG1355, Predicted dioxygenase; Belongs to the MEMO1 family.
    0.990
pgk
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
       0.864
AKB65323.1
Pyruvate formate lyase-activating enzyme 1.
 
     0.789
AKB65337.1
Molybdenum cofactor biosynthesis protein A.
 
     0.788
AKB64040.1
Endonuclease IV.
       0.520
AKB65517.1
Conserved transmembrane protein.
       0.520
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
       0.520
AKB64402.1
TldD protein, part of TldE/TldD proteolytic complex.
       0.501
AKB65525.1
GTP-binding protein, gtp1/obg family.
       0.450
AKB66063.1
Hypothetical protein.
     
 0.433
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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