| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKB64060.1 | AKB64061.1 | MSMAS_0864 | MSMAS_0865 | Zinc-finger protein. | 5,10-methylenetetrahydrofolate reductase. | 0.927 |
| AKB64060.1 | AKB64062.1 | MSMAS_0864 | MSMAS_0866 | Zinc-finger protein. | Coenzyme F420:L-glutamate ligase. | 0.668 |
| AKB64060.1 | AKB65796.1 | MSMAS_0864 | MSMAS_2600 | Zinc-finger protein. | CO dehydrogenase/acetyl-CoA synthase subunit delta, corrinoid iron-sulfur subcomplex small subunit. | 0.489 |
| AKB64060.1 | cdhD | MSMAS_0864 | MSMAS_0626 | Zinc-finger protein. | CO dehydrogenase/acetyl-CoA synthase subunit delta, corrinoid iron-sulfur subcomplex small subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. Probably maintains the overall quaternary structure of the ACDS complex. | 0.489 |
| AKB64060.1 | cdhE | MSMAS_0864 | MSMAS_0625 | Zinc-finger protein. | 5-tetrahydromethanopterin:corrinoid iron-sulfur protein methyltransferase; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. | 0.586 |
| AKB64060.1 | cdhE-2 | MSMAS_0864 | MSMAS_2601 | Zinc-finger protein. | 5-tetrahydromethanopterin:corrinoid iron-sulfur protein methyltransferase; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. | 0.586 |
| AKB64060.1 | folD | MSMAS_0864 | MSMAS_0862 | Zinc-finger protein. | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.606 |
| AKB64060.1 | glyA | MSMAS_0864 | MSMAS_0861 | Zinc-finger protein. | Serine hydroxymethyltransferase / L-threonine aldolase / L-allo-threonine aldolase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.595 |
| AKB64061.1 | AKB64060.1 | MSMAS_0865 | MSMAS_0864 | 5,10-methylenetetrahydrofolate reductase. | Zinc-finger protein. | 0.927 |
| AKB64061.1 | AKB64062.1 | MSMAS_0865 | MSMAS_0866 | 5,10-methylenetetrahydrofolate reductase. | Coenzyme F420:L-glutamate ligase. | 0.862 |
| AKB64061.1 | AKB64795.1 | MSMAS_0865 | MSMAS_1599 | 5,10-methylenetetrahydrofolate reductase. | Methionine gamma-lyase. | 0.940 |
| AKB64061.1 | AKB65796.1 | MSMAS_0865 | MSMAS_2600 | 5,10-methylenetetrahydrofolate reductase. | CO dehydrogenase/acetyl-CoA synthase subunit delta, corrinoid iron-sulfur subcomplex small subunit. | 0.873 |
| AKB64061.1 | cdhD | MSMAS_0865 | MSMAS_0626 | 5,10-methylenetetrahydrofolate reductase. | CO dehydrogenase/acetyl-CoA synthase subunit delta, corrinoid iron-sulfur subcomplex small subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. Probably maintains the overall quaternary structure of the ACDS complex. | 0.986 |
| AKB64061.1 | cdhE | MSMAS_0865 | MSMAS_0625 | 5,10-methylenetetrahydrofolate reductase. | 5-tetrahydromethanopterin:corrinoid iron-sulfur protein methyltransferase; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. | 0.969 |
| AKB64061.1 | cdhE-2 | MSMAS_0865 | MSMAS_2601 | 5,10-methylenetetrahydrofolate reductase. | 5-tetrahydromethanopterin:corrinoid iron-sulfur protein methyltransferase; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. | 0.969 |
| AKB64061.1 | folD | MSMAS_0865 | MSMAS_0862 | 5,10-methylenetetrahydrofolate reductase. | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.974 |
| AKB64061.1 | glyA | MSMAS_0865 | MSMAS_0861 | 5,10-methylenetetrahydrofolate reductase. | Serine hydroxymethyltransferase / L-threonine aldolase / L-allo-threonine aldolase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.985 |
| AKB64061.1 | thyA | MSMAS_0865 | MSMAS_0076 | 5,10-methylenetetrahydrofolate reductase. | Thymidylate synthase; May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily. | 0.944 |
| AKB64062.1 | AKB64060.1 | MSMAS_0866 | MSMAS_0864 | Coenzyme F420:L-glutamate ligase. | Zinc-finger protein. | 0.668 |
| AKB64062.1 | AKB64061.1 | MSMAS_0866 | MSMAS_0865 | Coenzyme F420:L-glutamate ligase. | 5,10-methylenetetrahydrofolate reductase. | 0.862 |
