| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKB64039.1 | AKB64061.1 | MSMAS_0843 | MSMAS_0865 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. | 5,10-methylenetetrahydrofolate reductase. | 0.878 |
| AKB64039.1 | AKB64795.1 | MSMAS_0843 | MSMAS_1599 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. | Methionine gamma-lyase. | 0.978 |
| AKB64039.1 | AKB66504.1 | MSMAS_0843 | MSMAS_3308 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. | 0.901 |
| AKB64039.1 | folD | MSMAS_0843 | MSMAS_0862 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.706 |
| AKB64039.1 | glyA | MSMAS_0843 | MSMAS_0861 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. | Serine hydroxymethyltransferase / L-threonine aldolase / L-allo-threonine aldolase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.444 |
| AKB64061.1 | AKB64039.1 | MSMAS_0865 | MSMAS_0843 | 5,10-methylenetetrahydrofolate reductase. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. | 0.878 |
| AKB64061.1 | AKB64795.1 | MSMAS_0865 | MSMAS_1599 | 5,10-methylenetetrahydrofolate reductase. | Methionine gamma-lyase. | 0.956 |
| AKB64061.1 | AKB65796.1 | MSMAS_0865 | MSMAS_2600 | 5,10-methylenetetrahydrofolate reductase. | CO dehydrogenase/acetyl-CoA synthase subunit delta, corrinoid iron-sulfur subcomplex small subunit. | 0.882 |
| AKB64061.1 | AKB66504.1 | MSMAS_0865 | MSMAS_3308 | 5,10-methylenetetrahydrofolate reductase. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. | 0.878 |
| AKB64061.1 | cdhD | MSMAS_0865 | MSMAS_0626 | 5,10-methylenetetrahydrofolate reductase. | CO dehydrogenase/acetyl-CoA synthase subunit delta, corrinoid iron-sulfur subcomplex small subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. Probably maintains the overall quaternary structure of the ACDS complex. | 0.987 |
| AKB64061.1 | cdhE | MSMAS_0865 | MSMAS_0625 | 5,10-methylenetetrahydrofolate reductase. | 5-tetrahydromethanopterin:corrinoid iron-sulfur protein methyltransferase; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. | 0.994 |
| AKB64061.1 | cdhE-2 | MSMAS_0865 | MSMAS_2601 | 5,10-methylenetetrahydrofolate reductase. | 5-tetrahydromethanopterin:corrinoid iron-sulfur protein methyltransferase; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. | 0.994 |
| AKB64061.1 | folD | MSMAS_0865 | MSMAS_0862 | 5,10-methylenetetrahydrofolate reductase. | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.974 |
| AKB64061.1 | glyA | MSMAS_0865 | MSMAS_0861 | 5,10-methylenetetrahydrofolate reductase. | Serine hydroxymethyltransferase / L-threonine aldolase / L-allo-threonine aldolase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.989 |
| AKB64061.1 | thyA | MSMAS_0865 | MSMAS_0076 | 5,10-methylenetetrahydrofolate reductase. | Thymidylate synthase; May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily. | 0.945 |
| AKB64795.1 | AKB64039.1 | MSMAS_1599 | MSMAS_0843 | Methionine gamma-lyase. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. | 0.978 |
| AKB64795.1 | AKB64061.1 | MSMAS_1599 | MSMAS_0865 | Methionine gamma-lyase. | 5,10-methylenetetrahydrofolate reductase. | 0.956 |
| AKB64795.1 | AKB66504.1 | MSMAS_1599 | MSMAS_3308 | Methionine gamma-lyase. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. | 0.978 |
| AKB64795.1 | glyA | MSMAS_1599 | MSMAS_0861 | Methionine gamma-lyase. | Serine hydroxymethyltransferase / L-threonine aldolase / L-allo-threonine aldolase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.507 |
| AKB65796.1 | AKB64061.1 | MSMAS_2600 | MSMAS_0865 | CO dehydrogenase/acetyl-CoA synthase subunit delta, corrinoid iron-sulfur subcomplex small subunit. | 5,10-methylenetetrahydrofolate reductase. | 0.882 |