Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AKB64106.1CoB--CoM heterodisulfide reductase subunit B. (83 aa)    
Predicted Functional Partners:
AKB63516.1
CoB--CoM heterodisulfide reductase subunit C.
 
 0.956
AKB64841.1
Coenzyme F420 hydrogenase subunit alpha.
  
 0.914
AKB64111.1
CoB--CoM heterodisulfide reductase subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
 
 0.858
AKB64844.1
Coenzyme F420 hydrogenase subunit beta.
 
 0.824
AKB66295.1
Formylmethanofuran dehydrogenase (molybdenum) subunit B.
 
 
 0.784
AKB65896.1
Formylmethanofuran dehydrogenase subunit B.
 
 
 0.783
AKB64464.1
Formylmethanofuran dehydrogenase subunit D.
 
 
 
 0.751
AKB65895.1
Formylmethanofuran dehydrogenase (tungsten) subunit D.
 
 
 
 0.743
AKB66296.1
Formylmethanofuran dehydrogenase (molybdenum) subunit D.
 
 
 
 0.736
AKB64843.1
Coenzyme F420 hydrogenase subunit gamma.
 
 0.732
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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