STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB64138.1Sulfite reductase, assimilatory-type. (223 aa)    
Predicted Functional Partners:
AKB63214.1
Hypothetical protein.
   
 0.930
AKB64545.1
Hypothetical protein.
  
 
 0.857
AKB64586.1
Rubredoxin; Belongs to the rubredoxin family.
  
 
 0.745
AKB64552.1
Iron-sulfur cluster binding protein.
   
 
 0.684
AKB64580.1
PUA-PAPS reductase like fusion.
 
   
 0.571
AKB64189.1
Uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family.
  
 0.557
AKB64139.1
Transcriptional regulator, HxlR family.
  
  
 0.556
AKB63533.1
Glutamine amidotransferase, class-II.
  
 
 0.547
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
  
 0.542
AKB65923.1
Homocysteine desulfhydrase.
  
 0.542
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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