Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AKB64192.1Cell division protein FtsH. (365 aa)    
Predicted Functional Partners:
AKB64191.1
Hypothetical protein.
       0.861
rpl2
LSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
  
 
 0.588
AKB66301.1
ABC-type tungstate transport system, ATP-binding protein.
  
     0.568
rpl21e
LSU ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
    
   0.559
rpl14
LSU ribosomal protein L23e (L14p); Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
  
   
 0.558
AKB65804.1
Hypothetical protein; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family.
  
     0.557
AKB63204.1
RNA ligase, family.
  
     0.543
AKB63556.1
Putative ABC transporter ATP-binding protein.
  
     0.526
AKB65800.1
YbbL ABC transporter ATP-binding protein.
  
     0.514
AKB63615.1
ATPase component NikO of energizing module of nickel ECF transporter; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.
  
     0.485
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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