Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
glmSGlucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (618 aa)    
Predicted Functional Partners:
glmM
Phosphomannomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
 
 
 0.999
AKB65909.1
Glucose-6-phosphate isomerase.
    
 0.984
AKB64194.1
Glucose-1-phosphate thymidylyltransferase.
  
 0.970
AKB63535.1
Glutamine synthetase type I.
 
 
 0.962
AKB64698.1
Glutamine synthetase type I.
 
 
 0.959
purQ
Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ a [...]
    
 0.953
carA
Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.
 
  
 0.940
AKB64197.1
Glucose-1-phosphate thymidylyltransferase.
 
  
 0.939
carB
Carbamoyl-phosphate synthase large chain; Belongs to the CarB family.
   
 0.934
AKB63845.1
Glutamate synthase [NADPH] small chain.
    
 0.928
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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