| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKB65756.1 | AKB66041.1 | MSMAS_2560 | MSMAS_2845 | LSU ribosomal protein L3e (L3p); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | DNA replication helicase protein MCM; Belongs to the MCM family. | 0.473 |
| AKB65756.1 | eif2g | MSMAS_2560 | MSMAS_0715 | LSU ribosomal protein L3e (L3p); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Eukaryotic translation initiation factor 2 gamma subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. | 0.966 |
| AKB65756.1 | eif6 | MSMAS_2560 | MSMAS_0498 | LSU ribosomal protein L3e (L3p); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Eukaryotic translation initiation factor 6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. | 0.986 |
| AKB65756.1 | fen | MSMAS_2560 | MSMAS_0399 | LSU ribosomal protein L3e (L3p); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] | 0.499 |
| AKB65756.1 | pcn | MSMAS_2560 | MSMAS_3265 | LSU ribosomal protein L3e (L3p); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | DNA polymerase sliding clamp protein PCNA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.677 |
| AKB65756.1 | rfcL | MSMAS_2560 | MSMAS_1048 | LSU ribosomal protein L3e (L3p); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 0.830 |
| AKB65756.1 | rpl7ae | MSMAS_2560 | MSMAS_2234 | LSU ribosomal protein L3e (L3p); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | LSU ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. | 0.999 |
| AKB65872.1 | AKB66041.1 | MSMAS_2676 | MSMAS_2845 | Archaeal DNA polymerase I. | DNA replication helicase protein MCM; Belongs to the MCM family. | 0.961 |
| AKB65872.1 | eif2g | MSMAS_2676 | MSMAS_0715 | Archaeal DNA polymerase I. | Eukaryotic translation initiation factor 2 gamma subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. | 0.404 |
| AKB65872.1 | eif6 | MSMAS_2676 | MSMAS_0498 | Archaeal DNA polymerase I. | Eukaryotic translation initiation factor 6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. | 0.594 |
| AKB65872.1 | fen | MSMAS_2676 | MSMAS_0399 | Archaeal DNA polymerase I. | Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] | 0.977 |
| AKB65872.1 | pcn | MSMAS_2676 | MSMAS_3265 | Archaeal DNA polymerase I. | DNA polymerase sliding clamp protein PCNA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.992 |
| AKB65872.1 | priL | MSMAS_2676 | MSMAS_3266 | Archaeal DNA polymerase I. | DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.988 |
| AKB65872.1 | priS | MSMAS_2676 | MSMAS_2872 | Archaeal DNA polymerase I. | DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] | 0.987 |
| AKB65872.1 | rfcL | MSMAS_2676 | MSMAS_1048 | Archaeal DNA polymerase I. | Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 0.913 |
| AKB66041.1 | AKB65756.1 | MSMAS_2845 | MSMAS_2560 | DNA replication helicase protein MCM; Belongs to the MCM family. | LSU ribosomal protein L3e (L3p); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.473 |
| AKB66041.1 | AKB65872.1 | MSMAS_2845 | MSMAS_2676 | DNA replication helicase protein MCM; Belongs to the MCM family. | Archaeal DNA polymerase I. | 0.961 |
| AKB66041.1 | eif2g | MSMAS_2845 | MSMAS_0715 | DNA replication helicase protein MCM; Belongs to the MCM family. | Eukaryotic translation initiation factor 2 gamma subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. | 0.625 |
| AKB66041.1 | eif6 | MSMAS_2845 | MSMAS_0498 | DNA replication helicase protein MCM; Belongs to the MCM family. | Eukaryotic translation initiation factor 6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. | 0.686 |
| AKB66041.1 | fen | MSMAS_2845 | MSMAS_0399 | DNA replication helicase protein MCM; Belongs to the MCM family. | Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] | 0.824 |