| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKB63211.1 | AKB63291.1 | MSMAS_0015 | MSMAS_0095 | Replication factor A (ssDNA-binding protein). | ATP-dependent DNA helicase RecQ. | 0.857 |
| AKB63211.1 | AKB64203.1 | MSMAS_0015 | MSMAS_1007 | Replication factor A (ssDNA-binding protein). | Replication protein A (two OB fold, one zinc finger). | 0.935 |
| AKB63211.1 | AKB65872.1 | MSMAS_0015 | MSMAS_2676 | Replication factor A (ssDNA-binding protein). | Archaeal DNA polymerase I. | 0.766 |
| AKB63211.1 | AKB66041.1 | MSMAS_0015 | MSMAS_2845 | Replication factor A (ssDNA-binding protein). | DNA replication helicase protein MCM; Belongs to the MCM family. | 0.815 |
| AKB63211.1 | AKB66124.1 | MSMAS_0015 | MSMAS_2928 | Replication factor A (ssDNA-binding protein). | Replication factor-A protein 1. | 0.942 |
| AKB63211.1 | fen | MSMAS_0015 | MSMAS_0399 | Replication factor A (ssDNA-binding protein). | Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] | 0.601 |
| AKB63211.1 | pcn | MSMAS_0015 | MSMAS_3265 | Replication factor A (ssDNA-binding protein). | DNA polymerase sliding clamp protein PCNA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.916 |
| AKB63211.1 | priL | MSMAS_0015 | MSMAS_3266 | Replication factor A (ssDNA-binding protein). | DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.711 |
| AKB63211.1 | priS | MSMAS_0015 | MSMAS_2872 | Replication factor A (ssDNA-binding protein). | DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] | 0.643 |
| AKB63211.1 | rfcL | MSMAS_0015 | MSMAS_1048 | Replication factor A (ssDNA-binding protein). | Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 0.799 |
| AKB63291.1 | AKB63211.1 | MSMAS_0095 | MSMAS_0015 | ATP-dependent DNA helicase RecQ. | Replication factor A (ssDNA-binding protein). | 0.857 |
| AKB63291.1 | AKB64203.1 | MSMAS_0095 | MSMAS_1007 | ATP-dependent DNA helicase RecQ. | Replication protein A (two OB fold, one zinc finger). | 0.857 |
| AKB63291.1 | AKB65872.1 | MSMAS_0095 | MSMAS_2676 | ATP-dependent DNA helicase RecQ. | Archaeal DNA polymerase I. | 0.688 |
| AKB63291.1 | AKB66041.1 | MSMAS_0095 | MSMAS_2845 | ATP-dependent DNA helicase RecQ. | DNA replication helicase protein MCM; Belongs to the MCM family. | 0.485 |
| AKB63291.1 | AKB66124.1 | MSMAS_0095 | MSMAS_2928 | ATP-dependent DNA helicase RecQ. | Replication factor-A protein 1. | 0.857 |
| AKB63291.1 | fen | MSMAS_0095 | MSMAS_0399 | ATP-dependent DNA helicase RecQ. | Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] | 0.980 |
| AKB63291.1 | pcn | MSMAS_0095 | MSMAS_3265 | ATP-dependent DNA helicase RecQ. | DNA polymerase sliding clamp protein PCNA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.889 |
| AKB63291.1 | priL | MSMAS_0095 | MSMAS_3266 | ATP-dependent DNA helicase RecQ. | DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.601 |
| AKB63291.1 | priS | MSMAS_0095 | MSMAS_2872 | ATP-dependent DNA helicase RecQ. | DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] | 0.414 |
| AKB63291.1 | rfcL | MSMAS_0095 | MSMAS_1048 | ATP-dependent DNA helicase RecQ. | Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 0.752 |
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