Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKB64256.1Inosine-5'-monophosphate dehydrogenase. (500 aa)    
Predicted Functional Partners:
AKB64257.1
Ferredoxin.
 
 
 0.999
AKB66247.1
Aspartate-semialdehyde dehydrogenase.
    
 0.983
AKB66504.1
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
     
 0.973
AKB64039.1
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
     
 0.963
AKB66505.1
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
     
 0.963
AKB65253.1
Hypothetical protein; Belongs to the UPF0280 family.
 
   
 0.949
AKB65190.1
Homoserine dehydrogenase.
     
 0.904
AKB65613.1
Adenosylhomocysteinase; Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine; Belongs to the adenosylhomocysteinase family.
     
  0.900
AKB65045.1
Hypothetical protein.
    
  0.803
AKB65468.1
Methylthiol:coenzyme M methyltransferase corrinoid protein.
    
  0.802
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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