| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKB63274.1 | AKB64357.1 | MSMAS_0078 | MSMAS_1161 | Mrr restriction system protein. | McrBC 5-methylcytosine restriction system component. | 0.429 |
| AKB64218.1 | AKB64356.1 | MSMAS_1022 | MSMAS_1160 | DNA-cytosine methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Hypothetical protein. | 0.424 |
| AKB64218.1 | AKB64357.1 | MSMAS_1022 | MSMAS_1161 | DNA-cytosine methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | McrBC 5-methylcytosine restriction system component. | 0.406 |
| AKB64356.1 | AKB64218.1 | MSMAS_1160 | MSMAS_1022 | Hypothetical protein. | DNA-cytosine methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.424 |
| AKB64356.1 | AKB64357.1 | MSMAS_1160 | MSMAS_1161 | Hypothetical protein. | McrBC 5-methylcytosine restriction system component. | 0.999 |
| AKB64356.1 | AKB64569.1 | MSMAS_1160 | MSMAS_1373 | Hypothetical protein. | Hypothetical protein. | 0.508 |
| AKB64357.1 | AKB63274.1 | MSMAS_1161 | MSMAS_0078 | McrBC 5-methylcytosine restriction system component. | Mrr restriction system protein. | 0.429 |
| AKB64357.1 | AKB64218.1 | MSMAS_1161 | MSMAS_1022 | McrBC 5-methylcytosine restriction system component. | DNA-cytosine methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.406 |
| AKB64357.1 | AKB64356.1 | MSMAS_1161 | MSMAS_1160 | McrBC 5-methylcytosine restriction system component. | Hypothetical protein. | 0.999 |
| AKB64357.1 | AKB64569.1 | MSMAS_1161 | MSMAS_1373 | McrBC 5-methylcytosine restriction system component. | Hypothetical protein. | 0.493 |
| AKB64357.1 | hacB | MSMAS_1161 | MSMAS_0664 | McrBC 5-methylcytosine restriction system component. | Coenzyme B synthesis from 2-oxoglutarate: steps 4, 7, 8, 11, and 12 (small subunit); Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis-homo(3)- aconitate. All these reactions are part of the biosynthesis path [...] | 0.562 |
| AKB64357.1 | leuC | MSMAS_1161 | MSMAS_0894 | McrBC 5-methylcytosine restriction system component. | Coenzyme B synthesis from 2-oxoglutarate: steps 4, 7, 8, 11, and 12 (large subunit); Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.620 |
| AKB64357.1 | leuC-2 | MSMAS_1161 | MSMAS_2326 | McrBC 5-methylcytosine restriction system component. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.620 |
| AKB64357.1 | leuD | MSMAS_1161 | MSMAS_3178 | McrBC 5-methylcytosine restriction system component. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. | 0.562 |
| AKB64569.1 | AKB64356.1 | MSMAS_1373 | MSMAS_1160 | Hypothetical protein. | Hypothetical protein. | 0.508 |
| AKB64569.1 | AKB64357.1 | MSMAS_1373 | MSMAS_1161 | Hypothetical protein. | McrBC 5-methylcytosine restriction system component. | 0.493 |
| hacB | AKB64357.1 | MSMAS_0664 | MSMAS_1161 | Coenzyme B synthesis from 2-oxoglutarate: steps 4, 7, 8, 11, and 12 (small subunit); Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis-homo(3)- aconitate. All these reactions are part of the biosynthesis path [...] | McrBC 5-methylcytosine restriction system component. | 0.562 |
| hacB | leuC | MSMAS_0664 | MSMAS_0894 | Coenzyme B synthesis from 2-oxoglutarate: steps 4, 7, 8, 11, and 12 (small subunit); Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis-homo(3)- aconitate. All these reactions are part of the biosynthesis path [...] | Coenzyme B synthesis from 2-oxoglutarate: steps 4, 7, 8, 11, and 12 (large subunit); Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.999 |
| hacB | leuC-2 | MSMAS_0664 | MSMAS_2326 | Coenzyme B synthesis from 2-oxoglutarate: steps 4, 7, 8, 11, and 12 (small subunit); Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis-homo(3)- aconitate. All these reactions are part of the biosynthesis path [...] | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.996 |
| hacB | leuD | MSMAS_0664 | MSMAS_3178 | Coenzyme B synthesis from 2-oxoglutarate: steps 4, 7, 8, 11, and 12 (small subunit); Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis-homo(3)- aconitate. All these reactions are part of the biosynthesis path [...] | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. | 0.712 |