Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB64389.1Cytochrome c-type biogenesis protein, archaeal, distantly related to heme lyase subunit CcmF. (353 aa)    
Predicted Functional Partners:
AKB64388.1
Putative cytochrome c biogenesis factor, archaeal.
     
 0.915
AKB65498.1
ABC transporter involved in cytochrome c biogenesis, CcmB subunit.
 
  
 0.888
AKB65499.1
Cytochrome c-type biogenesis protein CcmC, putative heme lyase for CcmE.
 
  
0.747
AKB63708.1
Hypothetical protein.
  
   
 0.693
carS
Phosphatidate cytidylyltransferase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
       0.656
AKB65497.1
ABC transporter involved in cytochrome c biogenesis, ATPase component CcmA.
 
   
 0.582
AKB63504.1
Putative thiol:disulfide oxidoreductase involved in cytochrome C-type biogenesis.
 
  
 0.526
AKB65802.1
Thioredoxin.
 
  
 0.515
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
       0.482
AKB65324.1
Ferrous iron transport protein A.
     
 0.474
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
Server load: low (8%) [HD]