Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB64578.1Hypothetical protein. (366 aa)    
Predicted Functional Partners:
thrS
Threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
     0.758
AKB63635.1
Periplasmic serine protease.
 
  
 0.618
AKB65036.1
Membrane protein, putative.
  
     0.457
AKB64665.1
Hypothetical protein.
  
     0.432
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
 
     0.429
AKB66458.1
Archaeosortase A.
  
    0.423
AKB63628.1
RecB family exonuclease.
 
     0.415
AKB64868.1
Sterol-regulatory element-binding protein intramembrane protease.
 
     0.413
AKB63250.1
Zn-ribbon containing protein.
  
     0.408
AKB63548.1
Hypothetical protein.
  
     0.407
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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