STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB64608.1Ancient conserved domain protein 4. (374 aa)    
Predicted Functional Partners:
guaAB
GMP synthase (glutamine-hydrolyzing), ATP pyrophosphatase subunit; Catalyzes the synthesis of GMP from XMP.
    
 0.589
AKB63603.1
IMP cyclohydrolase; Phosphoribosylaminoimidazolecarboxamide formyltransferase.
    
 0.540
AKB65409.1
NADH-quinone oxidoreductase subunit C/D.
       0.529
AKB65410.1
NADH-quinone oxidoreductase subunit C/D.
       0.529
AKB63261.1
tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
       0.512
AKB64607.1
Hemolysins and related protein containing CBS domains.
       0.506
surE
5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
  0.491
AKB64685.1
Glutamine amidotransferase class-I.
 
  
 0.469
AKB65705.1
GMP synthase (glutamine-hydrolyzing).
 
  
 0.465
AKB64657.1
ABC transporter, ATP-binding protein.
 
 
 0.403
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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