STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB64680.1Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps. (497 aa)    
Predicted Functional Partners:
AKB66266.1
Metal transporter, ZIP family.
  
 
 0.751
rpl2
LSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
 
 0.741
AKB66250.1
Aldo/keto reductase.
  
    0.717
AKB64438.1
Integral membrane protein.
 
  
 0.566
AKB63569.1
Kef-type transport system 2 (probable substrate potassium), subunit 2.
  
  
 0.534
AKB63573.1
Kef-type transport system 2 (probable substrate potassium), subunit 1.
  
  
 0.534
AKB65971.1
Glutathione-regulated potassium-efflux system protein KefC.
  
  
 0.534
gap
NAD(P)-dependent glyceraldehyde 3-phosphate dehydrogenase archaeal.
  
  
 0.526
AKB65153.1
Alcohol dehydrogenase.
  
    0.485
tbp
TATA-box binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
   
  
 0.474
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.