Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKB64692.1Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps. (473 aa)    
Predicted Functional Partners:
AKB64691.1
Transcriptional regulator, MarR family.
 
  
 0.762
rpl2
LSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
 
 0.741
gap
NAD(P)-dependent glyceraldehyde 3-phosphate dehydrogenase archaeal.
  
  
 0.526
tbp
TATA-box binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
   
  
 0.474
tbp-2
TATA-box binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
   
  
 0.474
tbp-3
TATA-box binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
   
  
 0.474
AKB65878.1
CobN component of cobalt chelatase involved in B12 biosynthesis.
  
  
 0.468
AKB66263.1
CobN-like chelatase BtuS for metalloporphyrine salvage.
  
  
 0.468
AKB66264.1
CobN-like chelatase BtuS for metalloporphyrine salvage.
  
  
 0.468
rpl15
LSU ribosomal protein L27Ae (L15p); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
   0.453
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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