| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKB63502.1 | AKB64741.1 | MSMAS_0306 | MSMAS_1545 | Cobalt-precorrin-8x methylmutase. | Cob(I)alamin adenosyltransferase. | 0.694 |
| AKB63502.1 | AKB65878.1 | MSMAS_0306 | MSMAS_2682 | Cobalt-precorrin-8x methylmutase. | CobN component of cobalt chelatase involved in B12 biosynthesis. | 0.606 |
| AKB63502.1 | AKB66263.1 | MSMAS_0306 | MSMAS_3067 | Cobalt-precorrin-8x methylmutase. | CobN-like chelatase BtuS for metalloporphyrine salvage. | 0.611 |
| AKB63502.1 | AKB66264.1 | MSMAS_0306 | MSMAS_3068 | Cobalt-precorrin-8x methylmutase. | CobN-like chelatase BtuS for metalloporphyrine salvage. | 0.611 |
| AKB63502.1 | cbiA-2 | MSMAS_0306 | MSMAS_3268 | Cobalt-precorrin-8x methylmutase. | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source. | 0.999 |
| AKB63502.1 | cobD | MSMAS_0306 | MSMAS_2627 | Cobalt-precorrin-8x methylmutase. | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.904 |
| AKB63502.1 | cobQ | MSMAS_0306 | MSMAS_1237 | Cobalt-precorrin-8x methylmutase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.995 |
| AKB63502.1 | cobS | MSMAS_0306 | MSMAS_2629 | Cobalt-precorrin-8x methylmutase. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.799 |
| AKB64324.1 | AKB64741.1 | MSMAS_1128 | MSMAS_1545 | Adenosylcobinamide amidohydrolase. | Cob(I)alamin adenosyltransferase. | 0.987 |
| AKB64324.1 | cobD | MSMAS_1128 | MSMAS_2627 | Adenosylcobinamide amidohydrolase. | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.989 |
| AKB64324.1 | cobQ | MSMAS_1128 | MSMAS_1237 | Adenosylcobinamide amidohydrolase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.962 |
| AKB64324.1 | cobS | MSMAS_1128 | MSMAS_2629 | Adenosylcobinamide amidohydrolase. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.891 |
| AKB64741.1 | AKB63502.1 | MSMAS_1545 | MSMAS_0306 | Cob(I)alamin adenosyltransferase. | Cobalt-precorrin-8x methylmutase. | 0.694 |
| AKB64741.1 | AKB64324.1 | MSMAS_1545 | MSMAS_1128 | Cob(I)alamin adenosyltransferase. | Adenosylcobinamide amidohydrolase. | 0.987 |
| AKB64741.1 | AKB65092.1 | MSMAS_1545 | MSMAS_1896 | Cob(I)alamin adenosyltransferase. | Ribonucleotide reductase of class II (coenzyme B12-dependent); Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.709 |
| AKB64741.1 | AKB65878.1 | MSMAS_1545 | MSMAS_2682 | Cob(I)alamin adenosyltransferase. | CobN component of cobalt chelatase involved in B12 biosynthesis. | 0.937 |
| AKB64741.1 | AKB66263.1 | MSMAS_1545 | MSMAS_3067 | Cob(I)alamin adenosyltransferase. | CobN-like chelatase BtuS for metalloporphyrine salvage. | 0.936 |
| AKB64741.1 | AKB66264.1 | MSMAS_1545 | MSMAS_3068 | Cob(I)alamin adenosyltransferase. | CobN-like chelatase BtuS for metalloporphyrine salvage. | 0.936 |
| AKB64741.1 | cbiA-2 | MSMAS_1545 | MSMAS_3268 | Cob(I)alamin adenosyltransferase. | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source. | 0.950 |
| AKB64741.1 | cobD | MSMAS_1545 | MSMAS_2627 | Cob(I)alamin adenosyltransferase. | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.979 |