Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB64761.1Transcriptional regulator, MarR family. (139 aa)    
Predicted Functional Partners:
lon
ATP-dependent protease La Type I; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
 
   
 0.789
AKB63675.1
Hypothetical protein.
 
  
 0.626
AKB64762.1
Hypothetical protein.
       0.559
AKB65235.1
ABC transporter, permease protein.
 
   
 0.557
AKB64642.1
Putative membrane protein.
 
     0.514
AKB64812.1
Putative membrane protein.
 
     0.506
AKB64639.1
Putative membrane protein.
 
     0.465
AKB64572.1
Ferredoxin.
 
 
 0.449
AKB63807.1
Multidrug resistance protein B.
 
   
 0.446
AKB64841.1
Coenzyme F420 hydrogenase subunit alpha.
 
   
 0.443
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
Server load: low (14%) [HD]