Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB64762.1Hypothetical protein. (185 aa)    
Predicted Functional Partners:
AKB65876.1
PQQ enzyme repeat domain protein.
 
 0.928
AKB64479.1
Putative ankyrin repeat protein.
 
 
 0.927
AKB65428.1
WD-domain containing protein.
 
 0.910
rpl40e
LSU ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.783
AKB63820.1
NMD protein affecting ribosome stability and mRNA decay.
  
 
 0.777
AKB65912.1
Malate dehydrogenase; Belongs to the LDH/MDH superfamily.
   
 
 0.731
AKB64721.1
Hypothetical protein.
   
 0.700
AKB64754.1
Hypothetical protein.
   
 0.700
AKB65531.1
GTPase Era.
   
 0.700
AKB66460.1
Transcription factor S.
   
 
 0.673
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
Server load: low (12%) [HD]