| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKB63219.1 | AKB63647.1 | MSMAS_0023 | MSMAS_0451 | Archaeosine tRNA-ribosyltransferase type 2. | AAA family ATPase; Belongs to the AAA ATPase family. | 0.456 |
| AKB63219.1 | AKB66123.1 | MSMAS_0023 | MSMAS_2927 | Archaeosine tRNA-ribosyltransferase type 2. | Glycerol dehydrogenase. | 0.711 |
| AKB63219.1 | top6A | MSMAS_0023 | MSMAS_2282 | Archaeosine tRNA-ribosyltransferase type 2. | DNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. | 0.462 |
| AKB63219.1 | topA | MSMAS_0023 | MSMAS_1612 | Archaeosine tRNA-ribosyltransferase type 2. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.421 |
| AKB63647.1 | AKB63219.1 | MSMAS_0451 | MSMAS_0023 | AAA family ATPase; Belongs to the AAA ATPase family. | Archaeosine tRNA-ribosyltransferase type 2. | 0.456 |
| AKB63647.1 | AKB66123.1 | MSMAS_0451 | MSMAS_2927 | AAA family ATPase; Belongs to the AAA ATPase family. | Glycerol dehydrogenase. | 0.447 |
| AKB63647.1 | topA | MSMAS_0451 | MSMAS_1612 | AAA family ATPase; Belongs to the AAA ATPase family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.432 |
| AKB64809.1 | topA | MSMAS_1613 | MSMAS_1612 | Hypothetical protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.521 |
| AKB66123.1 | AKB63219.1 | MSMAS_2927 | MSMAS_0023 | Glycerol dehydrogenase. | Archaeosine tRNA-ribosyltransferase type 2. | 0.711 |
| AKB66123.1 | AKB63647.1 | MSMAS_2927 | MSMAS_0451 | Glycerol dehydrogenase. | AAA family ATPase; Belongs to the AAA ATPase family. | 0.447 |
| AKB66123.1 | topA | MSMAS_2927 | MSMAS_1612 | Glycerol dehydrogenase. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.400 |
| top6A | AKB63219.1 | MSMAS_2282 | MSMAS_0023 | DNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. | Archaeosine tRNA-ribosyltransferase type 2. | 0.462 |
| top6A | topA | MSMAS_2282 | MSMAS_1612 | DNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.443 |
| topA | AKB63219.1 | MSMAS_1612 | MSMAS_0023 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Archaeosine tRNA-ribosyltransferase type 2. | 0.421 |
| topA | AKB63647.1 | MSMAS_1612 | MSMAS_0451 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | AAA family ATPase; Belongs to the AAA ATPase family. | 0.432 |
| topA | AKB64809.1 | MSMAS_1612 | MSMAS_1613 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Hypothetical protein. | 0.521 |
| topA | AKB66123.1 | MSMAS_1612 | MSMAS_2927 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Glycerol dehydrogenase. | 0.400 |
| topA | top6A | MSMAS_1612 | MSMAS_2282 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | DNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. | 0.443 |