STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB64817.1Fumarate hydratase class I, aerobic; L(+)-tartrate dehydratase beta subunit. (192 aa)    
Predicted Functional Partners:
AKB64818.1
Fumarate hydratase class I, aerobic; L(+)-tartrate dehydratase alpha subunit.
 0.999
AKB65912.1
Malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 
 0.994
AKB65270.1
NAD-dependent malic enzyme.
 
 0.989
AKB63221.1
Fe-S oxidoreductase; Homology to heterodisulfide reductase 2 iron-sulfur subunit.
 
  
 0.967
AKB66336.1
Citrate synthase (si).
  
 
 0.932
AKB65555.1
Succinate-semialdehyde dehydrogenase [NADP+].
  
 
 0.893
argH
Argininosuccinate lyase.
    
 0.831
AKB64254.1
Aspartate aminotransferase.
    
 0.812
AKB65527.1
Biosynthetic Aromatic amino acid aminotransferase alpha / Aspartate aminotransferase.
    
 0.812
AKB63902.1
Xanthosine/inosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
     
 0.805
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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