| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKB65105.1 | trpA | MSMAS_1909 | MSMAS_1905 | Anthranilate synthase, amidotransferase component. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.997 |
| AKB65105.1 | trpB | MSMAS_1909 | MSMAS_0964 | Anthranilate synthase, amidotransferase component. | Tryptophan synthase beta chain 1; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.552 |
| AKB65105.1 | trpB-2 | MSMAS_1909 | MSMAS_1904 | Anthranilate synthase, amidotransferase component. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.999 |
| AKB65105.1 | trpC | MSMAS_1909 | MSMAS_1903 | Anthranilate synthase, amidotransferase component. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.999 |
| AKB65105.1 | trpD | MSMAS_1909 | MSMAS_1906 | Anthranilate synthase, amidotransferase component. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
| AKB65105.1 | trpE | MSMAS_1909 | MSMAS_1908 | Anthranilate synthase, amidotransferase component. | Anthranilate synthase, aminase component; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high c [...] | 0.999 |
| AKB65105.1 | trpF | MSMAS_1909 | MSMAS_1371 | Anthranilate synthase, amidotransferase component. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.963 |
| AKB65105.1 | trpF-2 | MSMAS_1909 | MSMAS_1907 | Anthranilate synthase, amidotransferase component. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.991 |
| glyA | rpl2 | MSMAS_0861 | MSMAS_2557 | Serine hydroxymethyltransferase / L-threonine aldolase / L-allo-threonine aldolase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | LSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.859 |
| glyA | trpA | MSMAS_0861 | MSMAS_1905 | Serine hydroxymethyltransferase / L-threonine aldolase / L-allo-threonine aldolase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.955 |
| glyA | trpB | MSMAS_0861 | MSMAS_0964 | Serine hydroxymethyltransferase / L-threonine aldolase / L-allo-threonine aldolase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase beta chain 1; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.913 |
| glyA | trpB-2 | MSMAS_0861 | MSMAS_1904 | Serine hydroxymethyltransferase / L-threonine aldolase / L-allo-threonine aldolase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.960 |
| glyA | trpE | MSMAS_0861 | MSMAS_1908 | Serine hydroxymethyltransferase / L-threonine aldolase / L-allo-threonine aldolase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Anthranilate synthase, aminase component; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high c [...] | 0.563 |
| rpl2 | glyA | MSMAS_2557 | MSMAS_0861 | LSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | Serine hydroxymethyltransferase / L-threonine aldolase / L-allo-threonine aldolase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.859 |
| rpl2 | trpA | MSMAS_2557 | MSMAS_1905 | LSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.987 |
| rpl2 | trpB-2 | MSMAS_2557 | MSMAS_1904 | LSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.583 |
| trpA | AKB65105.1 | MSMAS_1905 | MSMAS_1909 | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Anthranilate synthase, amidotransferase component. | 0.997 |
| trpA | glyA | MSMAS_1905 | MSMAS_0861 | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Serine hydroxymethyltransferase / L-threonine aldolase / L-allo-threonine aldolase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.955 |
| trpA | rpl2 | MSMAS_1905 | MSMAS_2557 | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | LSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.987 |
| trpA | trpB | MSMAS_1905 | MSMAS_0964 | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Tryptophan synthase beta chain 1; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.999 |