nadK protein (Methanosarcina mazei) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

nadK

NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (275 aa)

Predicted Functional Partners:

AKB65140.1

0.994

nadE

0.938

AKB63893.1

0.928

AKB64603.1

0.927

AKB63879.1

0.925

surE

0.916

AKB65358.1

0.907

gap

0.892

AKB63604.1

0.815

AKB66482.1

0.802

Your Current Organism:

Methanosarcina mazei

NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKB63604.1	AKB64603.1	MSMAS_0408	MSMAS_1407	Dihydrolipoyl dehydrogenase.	Dihydrolipoamide dehydrogenase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.804
AKB63604.1	gap	MSMAS_0408	MSMAS_1945	Dihydrolipoyl dehydrogenase.	NAD(P)-dependent glyceraldehyde 3-phosphate dehydrogenase archaeal.	0.407
AKB63604.1	nadK	MSMAS_0408	MSMAS_1943	Dihydrolipoyl dehydrogenase.	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.815
AKB63879.1	AKB63893.1	MSMAS_0683	MSMAS_0697	Nicotinamide-nucleotide adenylyltransferase, NadM family.	NAD synthetase.	0.966
AKB63879.1	AKB65358.1	MSMAS_0683	MSMAS_2162	Nicotinamide-nucleotide adenylyltransferase, NadM family.	NADH pyrophosphatase.	0.903
AKB63879.1	nadE	MSMAS_0683	MSMAS_0857	Nicotinamide-nucleotide adenylyltransferase, NadM family.	NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	0.970
AKB63879.1	nadK	MSMAS_0683	MSMAS_1943	Nicotinamide-nucleotide adenylyltransferase, NadM family.	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.925
AKB63879.1	surE	MSMAS_0683	MSMAS_3272	Nicotinamide-nucleotide adenylyltransferase, NadM family.	5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.	0.957
AKB63893.1	AKB63879.1	MSMAS_0697	MSMAS_0683	NAD synthetase.	Nicotinamide-nucleotide adenylyltransferase, NadM family.	0.966
AKB63893.1	AKB65358.1	MSMAS_0697	MSMAS_2162	NAD synthetase.	NADH pyrophosphatase.	0.950
AKB63893.1	nadE	MSMAS_0697	MSMAS_0857	NAD synthetase.	NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	0.910
AKB63893.1	nadK	MSMAS_0697	MSMAS_1943	NAD synthetase.	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.928
AKB64603.1	AKB63604.1	MSMAS_1407	MSMAS_0408	Dihydrolipoamide dehydrogenase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Dihydrolipoyl dehydrogenase.	0.804
AKB64603.1	nadK	MSMAS_1407	MSMAS_1943	Dihydrolipoamide dehydrogenase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.927
AKB65140.1	gap	MSMAS_1944	MSMAS_1945	Inositol-1-monophosphatase.	NAD(P)-dependent glyceraldehyde 3-phosphate dehydrogenase archaeal.	0.942
AKB65140.1	nadK	MSMAS_1944	MSMAS_1943	Inositol-1-monophosphatase.	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.994
AKB65358.1	AKB63879.1	MSMAS_2162	MSMAS_0683	NADH pyrophosphatase.	Nicotinamide-nucleotide adenylyltransferase, NadM family.	0.903
AKB65358.1	AKB63893.1	MSMAS_2162	MSMAS_0697	NADH pyrophosphatase.	NAD synthetase.	0.950
AKB65358.1	nadE	MSMAS_2162	MSMAS_0857	NADH pyrophosphatase.	NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	0.950
AKB65358.1	nadK	MSMAS_2162	MSMAS_1943	NADH pyrophosphatase.	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.907

page 1 of 3

Server load: low (20%) [HD]

Permalink

Network

Neighborhood

Databases

Fusion

Textmining

Co-occurrence

Experiments

Co-expression

© STRING Consortium 2026

Credits

Access

Info

About