STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB65180.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (805 aa)    
Predicted Functional Partners:
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
  
 0.979
AKB63798.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.975
AKB66517.1
Pyruvate:ferredoxin oxidoreductase, gamma subunit.
  
 
 0.974
AKB66518.1
Pyruvate:ferredoxin oxidoreductase, delta subunit.
    
 0.974
AKB66519.1
Pyruvate:ferredoxin oxidoreductase, alpha subunit.
    
 0.974
AKB66520.1
Pyruvate:ferredoxin oxidoreductase, beta subunit.
    
 0.974
AKB65270.1
NAD-dependent malic enzyme.
    
 0.973
ppcA
Phosphoenolpyruvate carboxylase, archaeal; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family.
     
 0.971
AKB64079.1
2-oxoglutarate oxidoreductase, alpha subunit.
    
 0.965
AKB64080.1
2-oxoglutarate oxidoreductase, beta subunit.
    
 0.951
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.