AKB65216.1 protein (Methanosarcina mazei) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

AKB65216.1

Mobile element protein. (62 aa)

Predicted Functional Partners:

AKB64458.1

0.798

AKB65215.1

0.773

AKB64479.1

0.704

rpl2

0.675

rpl40e

0.662

AKB65475.1

0.622

ndk

0.618

AKB65093.1

0.616

dnaJ

0.584

AKB66477.1

0.584

Your Current Organism:

Methanosarcina mazei

NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKB64458.1	AKB64479.1	MSMAS_1262	MSMAS_1283	Deacetylase.	Putative ankyrin repeat protein.	0.890
AKB64458.1	AKB65093.1	MSMAS_1262	MSMAS_1897	Deacetylase.	Peptidyl-prolyl cis-trans isomerase.	0.838
AKB64458.1	AKB65215.1	MSMAS_1262	MSMAS_2019	Deacetylase.	Mobile element protein.	0.798
AKB64458.1	AKB65216.1	MSMAS_1262	MSMAS_2020	Deacetylase.	Mobile element protein.	0.798
AKB64458.1	AKB65475.1	MSMAS_1262	MSMAS_2279	Deacetylase.	Chaperone protein.	0.938
AKB64458.1	AKB66477.1	MSMAS_1262	MSMAS_3281	Deacetylase.	Chaperone protein.	0.780
AKB64458.1	dnaJ	MSMAS_1262	MSMAS_2197	Deacetylase.	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.780
AKB64458.1	ndk	MSMAS_1262	MSMAS_2237	Deacetylase.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.	0.836
AKB64458.1	rpl2	MSMAS_1262	MSMAS_2557	Deacetylase.	LSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	0.683
AKB64458.1	rpl40e	MSMAS_1262	MSMAS_0362	Deacetylase.	LSU ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.	0.892
AKB64479.1	AKB64458.1	MSMAS_1283	MSMAS_1262	Putative ankyrin repeat protein.	Deacetylase.	0.890
AKB64479.1	AKB65093.1	MSMAS_1283	MSMAS_1897	Putative ankyrin repeat protein.	Peptidyl-prolyl cis-trans isomerase.	0.871
AKB64479.1	AKB65215.1	MSMAS_1283	MSMAS_2019	Putative ankyrin repeat protein.	Mobile element protein.	0.704
AKB64479.1	AKB65216.1	MSMAS_1283	MSMAS_2020	Putative ankyrin repeat protein.	Mobile element protein.	0.704
AKB64479.1	AKB65475.1	MSMAS_1283	MSMAS_2279	Putative ankyrin repeat protein.	Chaperone protein.	0.814
AKB64479.1	AKB66477.1	MSMAS_1283	MSMAS_3281	Putative ankyrin repeat protein.	Chaperone protein.	0.796
AKB64479.1	dnaJ	MSMAS_1283	MSMAS_2197	Putative ankyrin repeat protein.	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.796
AKB64479.1	ndk	MSMAS_1283	MSMAS_2237	Putative ankyrin repeat protein.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.	0.870
AKB64479.1	rpl2	MSMAS_1283	MSMAS_2557	Putative ankyrin repeat protein.	LSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	0.865
AKB64479.1	rpl40e	MSMAS_1283	MSMAS_0362	Putative ankyrin repeat protein.	LSU ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.	0.912