STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB65270.1NAD-dependent malic enzyme. (439 aa)    
Predicted Functional Partners:
AKB64817.1
Fumarate hydratase class I, aerobic; L(+)-tartrate dehydratase beta subunit.
 
 0.989
AKB65180.1
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.982
AKB65912.1
Malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.974
AKB66106.1
Pyruvate,phosphate dikinase.
    
 0.973
AKB63798.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.967
AKB64818.1
Fumarate hydratase class I, aerobic; L(+)-tartrate dehydratase alpha subunit.
 
 
 0.963
AKB64079.1
2-oxoglutarate oxidoreductase, alpha subunit.
  
 
 0.942
AKB64080.1
2-oxoglutarate oxidoreductase, beta subunit.
    
 0.942
AKB66049.1
Pyruvate carboxyl transferase subunit A.
  
 0.940
AKB66050.1
Pyruvate carboxyl transferase subunit B.
    
 0.935
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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