| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKB63702.1 | AKB65271.1 | MSMAS_0506 | MSMAS_2075 | Proteasome-activating AAA-ATPase (PAN), archaeal; Belongs to the AAA ATPase family. | Mov34 family protein. | 0.955 |
| AKB63702.1 | pan | MSMAS_0506 | MSMAS_0294 | Proteasome-activating AAA-ATPase (PAN), archaeal; Belongs to the AAA ATPase family. | Proteasome-activating AAA-ATPase (PAN), archaeal; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone pr [...] | 0.905 |
| AKB63702.1 | psmA | MSMAS_0506 | MSMAS_2088 | Proteasome-activating AAA-ATPase (PAN), archaeal; Belongs to the AAA ATPase family. | Proteasome subunit alpha, archaeal; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.927 |
| AKB63702.1 | psmB | MSMAS_0506 | MSMAS_0620 | Proteasome-activating AAA-ATPase (PAN), archaeal; Belongs to the AAA ATPase family. | Proteasome subunit beta, archaeal; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.909 |
| AKB63702.1 | rpl2 | MSMAS_0506 | MSMAS_2557 | Proteasome-activating AAA-ATPase (PAN), archaeal; Belongs to the AAA ATPase family. | LSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.748 |
| AKB63702.1 | rpl40e | MSMAS_0506 | MSMAS_0362 | Proteasome-activating AAA-ATPase (PAN), archaeal; Belongs to the AAA ATPase family. | LSU ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.872 |
| AKB63702.1 | rps3 | MSMAS_0506 | MSMAS_2554 | Proteasome-activating AAA-ATPase (PAN), archaeal; Belongs to the AAA ATPase family. | SSU ribosomal protein S3e (S3p); Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. | 0.578 |
| AKB65271.1 | AKB63702.1 | MSMAS_2075 | MSMAS_0506 | Mov34 family protein. | Proteasome-activating AAA-ATPase (PAN), archaeal; Belongs to the AAA ATPase family. | 0.955 |
| AKB65271.1 | AKB66072.1 | MSMAS_2075 | MSMAS_2876 | Mov34 family protein. | Eukaryotic translation initiation factor 2 alpha subunit. | 0.976 |
| AKB65271.1 | eif2b | MSMAS_2075 | MSMAS_3192 | Mov34 family protein. | Eukaryotic translation initiation factor 2 beta subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. | 0.967 |
| AKB65271.1 | pan | MSMAS_2075 | MSMAS_0294 | Mov34 family protein. | Proteasome-activating AAA-ATPase (PAN), archaeal; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone pr [...] | 0.955 |
| AKB65271.1 | psmA | MSMAS_2075 | MSMAS_2088 | Mov34 family protein. | Proteasome subunit alpha, archaeal; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.929 |
| AKB65271.1 | psmB | MSMAS_2075 | MSMAS_0620 | Mov34 family protein. | Proteasome subunit beta, archaeal; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.929 |
| AKB65271.1 | rpl2 | MSMAS_2075 | MSMAS_2557 | Mov34 family protein. | LSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.966 |
| AKB65271.1 | rpl40e | MSMAS_2075 | MSMAS_0362 | Mov34 family protein. | LSU ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.988 |
| AKB65271.1 | rps24e | MSMAS_2075 | MSMAS_0710 | Mov34 family protein. | SSU ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. | 0.930 |
| AKB65271.1 | rps3 | MSMAS_2075 | MSMAS_2554 | Mov34 family protein. | SSU ribosomal protein S3e (S3p); Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. | 0.943 |
| AKB66072.1 | AKB65271.1 | MSMAS_2876 | MSMAS_2075 | Eukaryotic translation initiation factor 2 alpha subunit. | Mov34 family protein. | 0.976 |
| AKB66072.1 | eif2b | MSMAS_2876 | MSMAS_3192 | Eukaryotic translation initiation factor 2 alpha subunit. | Eukaryotic translation initiation factor 2 beta subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. | 0.999 |
| AKB66072.1 | rpl2 | MSMAS_2876 | MSMAS_2557 | Eukaryotic translation initiation factor 2 alpha subunit. | LSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.999 |