psmA protein (Methanosarcina mazei) - STRING interaction network

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psmA

Proteasome subunit alpha, archaeal; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (249 aa)

Predicted Functional Partners:

AKB65283.1

0.969

psmB

0.963

rrp4

0.951

pan

0.922

AKB63702.1

0.912

rpl37ae

0.910

rrp42

0.908

AKB65271.1

0.902

rpl15e

0.899

AKB65281.1

0.829

Your Current Organism:

Methanosarcina mazei

NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKB63702.1	AKB65271.1	MSMAS_0506	MSMAS_2075	Proteasome-activating AAA-ATPase (PAN), archaeal; Belongs to the AAA ATPase family.	Mov34 family protein.	0.942
AKB63702.1	pan	MSMAS_0506	MSMAS_0294	Proteasome-activating AAA-ATPase (PAN), archaeal; Belongs to the AAA ATPase family.	Proteasome-activating AAA-ATPase (PAN), archaeal; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone pr [...]	0.905
AKB63702.1	psmA	MSMAS_0506	MSMAS_2088	Proteasome-activating AAA-ATPase (PAN), archaeal; Belongs to the AAA ATPase family.	Proteasome subunit alpha, archaeal; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.	0.912
AKB63702.1	psmB	MSMAS_0506	MSMAS_0620	Proteasome-activating AAA-ATPase (PAN), archaeal; Belongs to the AAA ATPase family.	Proteasome subunit beta, archaeal; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.	0.905
AKB63702.1	rpl15e	MSMAS_0506	MSMAS_2092	Proteasome-activating AAA-ATPase (PAN), archaeal; Belongs to the AAA ATPase family.	LSU ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family.	0.427
AKB65271.1	AKB63702.1	MSMAS_2075	MSMAS_0506	Mov34 family protein.	Proteasome-activating AAA-ATPase (PAN), archaeal; Belongs to the AAA ATPase family.	0.942
AKB65271.1	pan	MSMAS_2075	MSMAS_0294	Mov34 family protein.	Proteasome-activating AAA-ATPase (PAN), archaeal; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone pr [...]	0.942
AKB65271.1	psmA	MSMAS_2075	MSMAS_2088	Mov34 family protein.	Proteasome subunit alpha, archaeal; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.	0.902
AKB65271.1	psmB	MSMAS_2075	MSMAS_0620	Mov34 family protein.	Proteasome subunit beta, archaeal; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.	0.902
AKB65271.1	rpl15e	MSMAS_2075	MSMAS_2092	Mov34 family protein.	LSU ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family.	0.672
AKB65271.1	rpl37ae	MSMAS_2075	MSMAS_2083	Mov34 family protein.	LSU ribosomal protein L37Ae; Binds to the 23S rRNA.	0.555
AKB65281.1	AKB65283.1	MSMAS_2085	MSMAS_2087	Ribonuclease PH.	Shwachman-Bodian-Diamond syndrome protein; Predicted exosome subunit.	0.880
AKB65281.1	psmA	MSMAS_2085	MSMAS_2088	Ribonuclease PH.	Proteasome subunit alpha, archaeal; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.	0.829
AKB65281.1	rpl15e	MSMAS_2085	MSMAS_2092	Ribonuclease PH.	LSU ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family.	0.725
AKB65281.1	rpl37ae	MSMAS_2085	MSMAS_2083	Ribonuclease PH.	LSU ribosomal protein L37Ae; Binds to the 23S rRNA.	0.933
AKB65281.1	rrp4	MSMAS_2085	MSMAS_2086	Ribonuclease PH.	Putative exosome complex RNA-binding protein 1; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.	0.999
AKB65281.1	rrp42	MSMAS_2085	MSMAS_2084	Ribonuclease PH.	Putative exosome complex exonuclease 2; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.	0.999
AKB65283.1	AKB65281.1	MSMAS_2087	MSMAS_2085	Shwachman-Bodian-Diamond syndrome protein; Predicted exosome subunit.	Ribonuclease PH.	0.880
AKB65283.1	psmA	MSMAS_2087	MSMAS_2088	Shwachman-Bodian-Diamond syndrome protein; Predicted exosome subunit.	Proteasome subunit alpha, archaeal; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.	0.969
AKB65283.1	psmB	MSMAS_2087	MSMAS_0620	Shwachman-Bodian-Diamond syndrome protein; Predicted exosome subunit.	Proteasome subunit beta, archaeal; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.	0.443