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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB65499.1Cytochrome c-type biogenesis protein CcmC, putative heme lyase for CcmE. (237 aa)    
Predicted Functional Partners:
AKB65498.1
ABC transporter involved in cytochrome c biogenesis, CcmB subunit.
 
 0.999
AKB65497.1
ABC transporter involved in cytochrome c biogenesis, ATPase component CcmA.
 
  
 0.868
AKB65409.1
NADH-quinone oxidoreductase subunit C/D.
  
  
 0.800
AKB65410.1
NADH-quinone oxidoreductase subunit C/D.
  
  
 0.800
AKB64389.1
Cytochrome c-type biogenesis protein, archaeal, distantly related to heme lyase subunit CcmF.
 
  
0.711
AKB64189.1
Uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family.
  
 
  0.647
rpl2
LSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
  
  
 0.615
AKB64188.1
Uroporphyrinogen-III synthase.
  
  
 0.614
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
  
  
 0.607
fpoH
FPO subunit H; FPO shuttles electrons from F(420)H(2), via FAD and iron- sulfur (Fe-S) centers, to quinones in the F(420)H(2):heterodisulfide oxidoreduction chain. The immediate electron acceptor for the enzyme in this species is believed to be methanophenazine. Couples the redox reaction to proton translocation (for every two electrons transferred, 0.9 hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
  
 0.586
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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