Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AKB65518.1Serine/threonine kinase. (130 aa)    
Predicted Functional Partners:
AKB63913.1
Integral membrane protein.
  
    0.472
AKB64479.1
Putative ankyrin repeat protein.
 
  
 0.439
AKB64603.1
Dihydrolipoamide dehydrogenase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
  
 0.434
AKB65519.1
Hypothetical protein.
       0.432
AKB65578.1
[NiFe] hydrogenase metallocenter assembly protein HypE.
 
     0.428
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
    
  0.426
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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