| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKB63603.1 | AKB65537.1 | MSMAS_0407 | MSMAS_2341 | IMP cyclohydrolase; Phosphoribosylaminoimidazolecarboxamide formyltransferase. | Cytidine kinase; Belongs to the carbohydrate kinase PfkB family. | 0.926 |
| AKB63603.1 | guaAA | MSMAS_0407 | MSMAS_0046 | IMP cyclohydrolase; Phosphoribosylaminoimidazolecarboxamide formyltransferase. | GMP synthase (glutamine-hydrolyzing), amidotransferase subunit; Catalyzes the synthesis of GMP from XMP. | 0.490 |
| AKB63603.1 | guaAB | MSMAS_0407 | MSMAS_0094 | IMP cyclohydrolase; Phosphoribosylaminoimidazolecarboxamide formyltransferase. | GMP synthase (glutamine-hydrolyzing), ATP pyrophosphatase subunit; Catalyzes the synthesis of GMP from XMP. | 0.799 |
| AKB63603.1 | hisA | MSMAS_0407 | MSMAS_3164 | IMP cyclohydrolase; Phosphoribosylaminoimidazolecarboxamide formyltransferase. | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. | 0.831 |
| AKB63603.1 | hpt | MSMAS_0407 | MSMAS_2811 | IMP cyclohydrolase; Phosphoribosylaminoimidazolecarboxamide formyltransferase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | 0.975 |
| AKB63603.1 | purA | MSMAS_0407 | MSMAS_0504 | IMP cyclohydrolase; Phosphoribosylaminoimidazolecarboxamide formyltransferase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.995 |
| AKB63603.1 | surE | MSMAS_0407 | MSMAS_3272 | IMP cyclohydrolase; Phosphoribosylaminoimidazolecarboxamide formyltransferase. | 5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.942 |
| AKB65516.1 | AKB65537.1 | MSMAS_2320 | MSMAS_2341 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Cytidine kinase; Belongs to the carbohydrate kinase PfkB family. | 0.822 |
| AKB65516.1 | AKB66259.1 | MSMAS_2320 | MSMAS_3063 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Ribose-1,5-bisphosphate isomerase; Belongs to the eIF-2B alpha/beta/delta subunits family. | 0.569 |
| AKB65516.1 | cmk | MSMAS_2320 | MSMAS_2531 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Cytidylate kinase. | 0.589 |
| AKB65516.1 | guaAB | MSMAS_2320 | MSMAS_0094 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | GMP synthase (glutamine-hydrolyzing), ATP pyrophosphatase subunit; Catalyzes the synthesis of GMP from XMP. | 0.568 |
| AKB65516.1 | hpt | MSMAS_2320 | MSMAS_2811 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | 0.867 |
| AKB65516.1 | purA | MSMAS_2320 | MSMAS_0504 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.469 |
| AKB65516.1 | surE | MSMAS_2320 | MSMAS_3272 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | 5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.726 |
| AKB65537.1 | AKB63603.1 | MSMAS_2341 | MSMAS_0407 | Cytidine kinase; Belongs to the carbohydrate kinase PfkB family. | IMP cyclohydrolase; Phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.926 |
| AKB65537.1 | AKB65516.1 | MSMAS_2341 | MSMAS_2320 | Cytidine kinase; Belongs to the carbohydrate kinase PfkB family. | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | 0.822 |
| AKB65537.1 | AKB66259.1 | MSMAS_2341 | MSMAS_3063 | Cytidine kinase; Belongs to the carbohydrate kinase PfkB family. | Ribose-1,5-bisphosphate isomerase; Belongs to the eIF-2B alpha/beta/delta subunits family. | 0.792 |
| AKB65537.1 | cmk | MSMAS_2341 | MSMAS_2531 | Cytidine kinase; Belongs to the carbohydrate kinase PfkB family. | Cytidylate kinase. | 0.922 |
| AKB65537.1 | guaAA | MSMAS_2341 | MSMAS_0046 | Cytidine kinase; Belongs to the carbohydrate kinase PfkB family. | GMP synthase (glutamine-hydrolyzing), amidotransferase subunit; Catalyzes the synthesis of GMP from XMP. | 0.912 |
| AKB65537.1 | guaAB | MSMAS_2341 | MSMAS_0094 | Cytidine kinase; Belongs to the carbohydrate kinase PfkB family. | GMP synthase (glutamine-hydrolyzing), ATP pyrophosphatase subunit; Catalyzes the synthesis of GMP from XMP. | 0.926 |