STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB65539.1Hypothetical protein. (93 aa)    
Predicted Functional Partners:
AKB66006.1
Diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 1; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family.
  
  
  0.736
dphB
Diphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.
 
     0.698
AKB66124.1
Replication factor-A protein 1.
  
     0.655
rpl44e
LSU ribosomal protein L44e; Binds to the 23S rRNA.
  
     0.643
AKB65536.1
Hypothetical protein; COG2102: Predicted ATPases of PP-loop superfamily; IPR002761: Domain of unknown function DUF71.
 
  
  0.636
AKB66123.1
Glycerol dehydrogenase.
  
     0.625
AKB65538.1
Hypothetical protein; Belongs to the UPF0212 family.
 
     0.615
AKB66163.1
Hypothetical protein.
  
     0.603
AKB64055.1
HTH DNA-binding protein.
  
     0.596
AKB64401.1
ATP-dependent protease La Type I; Belongs to the peptidase S16 family.
  
     0.591
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.