| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKB63676.1 | AKB65546.1 | MSMAS_0480 | MSMAS_2350 | 5-amino-6-(5-phosphoribosylamino)uracil reductase. | Hydrolase, HAD superfamily. | 0.404 |
| AKB63676.1 | AKB65547.1 | MSMAS_0480 | MSMAS_2351 | 5-amino-6-(5-phosphoribosylamino)uracil reductase. | Hydrolase, HAD superfamily. | 0.404 |
| AKB65516.1 | AKB65546.1 | MSMAS_2320 | MSMAS_2350 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Hydrolase, HAD superfamily. | 0.526 |
| AKB65516.1 | AKB65547.1 | MSMAS_2320 | MSMAS_2351 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Hydrolase, HAD superfamily. | 0.463 |
| AKB65546.1 | AKB63676.1 | MSMAS_2350 | MSMAS_0480 | Hydrolase, HAD superfamily. | 5-amino-6-(5-phosphoribosylamino)uracil reductase. | 0.404 |
| AKB65546.1 | AKB65516.1 | MSMAS_2350 | MSMAS_2320 | Hydrolase, HAD superfamily. | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | 0.526 |
| AKB65546.1 | AKB65547.1 | MSMAS_2350 | MSMAS_2351 | Hydrolase, HAD superfamily. | Hydrolase, HAD superfamily. | 0.697 |
| AKB65546.1 | AKB65548.1 | MSMAS_2350 | MSMAS_2352 | Hydrolase, HAD superfamily. | GTP cyclohydrolase III (methanopterin). | 0.429 |
| AKB65546.1 | glyA | MSMAS_2350 | MSMAS_0861 | Hydrolase, HAD superfamily. | Serine hydroxymethyltransferase / L-threonine aldolase / L-allo-threonine aldolase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.427 |
| AKB65547.1 | AKB63676.1 | MSMAS_2351 | MSMAS_0480 | Hydrolase, HAD superfamily. | 5-amino-6-(5-phosphoribosylamino)uracil reductase. | 0.404 |
| AKB65547.1 | AKB65516.1 | MSMAS_2351 | MSMAS_2320 | Hydrolase, HAD superfamily. | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | 0.463 |
| AKB65547.1 | AKB65546.1 | MSMAS_2351 | MSMAS_2350 | Hydrolase, HAD superfamily. | Hydrolase, HAD superfamily. | 0.697 |
| AKB65547.1 | AKB65548.1 | MSMAS_2351 | MSMAS_2352 | Hydrolase, HAD superfamily. | GTP cyclohydrolase III (methanopterin). | 0.466 |
| AKB65547.1 | glyA | MSMAS_2351 | MSMAS_0861 | Hydrolase, HAD superfamily. | Serine hydroxymethyltransferase / L-threonine aldolase / L-allo-threonine aldolase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.427 |
| AKB65548.1 | AKB65546.1 | MSMAS_2352 | MSMAS_2350 | GTP cyclohydrolase III (methanopterin). | Hydrolase, HAD superfamily. | 0.429 |
| AKB65548.1 | AKB65547.1 | MSMAS_2352 | MSMAS_2351 | GTP cyclohydrolase III (methanopterin). | Hydrolase, HAD superfamily. | 0.466 |
| glyA | AKB65546.1 | MSMAS_0861 | MSMAS_2350 | Serine hydroxymethyltransferase / L-threonine aldolase / L-allo-threonine aldolase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Hydrolase, HAD superfamily. | 0.427 |
| glyA | AKB65547.1 | MSMAS_0861 | MSMAS_2351 | Serine hydroxymethyltransferase / L-threonine aldolase / L-allo-threonine aldolase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Hydrolase, HAD superfamily. | 0.427 |