STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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hypA[NiFe] hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (137 aa)    
Predicted Functional Partners:
AKB65579.1
[NiFe] hydrogenase nickel incorporation-associated protein HypB.
 
 0.985
AKB65581.1
[NiFe] hydrogenase metallocenter assembly protein HypD.
 
  
 0.979
AKB65718.1
[NiFe] hydrogenase nickel incorporation-associated protein HypB.
 
 0.959
AKB64841.1
Coenzyme F420 hydrogenase subunit alpha.
 
 
 0.944
AKB65578.1
[NiFe] hydrogenase metallocenter assembly protein HypE.
 
  
 0.943
AKB63505.1
Cytosolic Fe-S cluster assembling factor NBP35; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
   
 
 0.903
AKB63721.1
[NiFe] hydrogenase metallocenter assembly protein HypF.
 
   
 0.896
AKB65582.1
[NiFe] hydrogenase metallocenter assembly protein HypC.
 
  
 0.887
AKB63432.1
Hydrogenase, group 4, HycE subunit, putative.
  
 
 0.848
AKB65584.1
Methanophenazine hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.796
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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