STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB65613.1Adenosylhomocysteinase; Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine; Belongs to the adenosylhomocysteinase family. (411 aa)    
Predicted Functional Partners:
AKB64039.1
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
  
 
 0.978
AKB66504.1
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
  
 
 0.978
AKB66505.1
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
  
 
 0.978
AKB64218.1
DNA-cytosine methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
    
 0.934
AKB64256.1
Inosine-5'-monophosphate dehydrogenase.
     
  0.900
AKB64257.1
Ferredoxin.
     
  0.900
AKB65468.1
Methylthiol:coenzyme M methyltransferase corrinoid protein.
    
 0.865
AKB64795.1
Methionine gamma-lyase.
  
 0.860
AKB65190.1
Homoserine dehydrogenase.
  
 
 0.845
AKB65469.1
Methylcobalamin:coenzyme M methyltransferase, methanol-specific.
   
 
 0.815
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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