STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB65706.1KEOPS complex Cgi121-like subunit. (174 aa)    
Predicted Functional Partners:
AKB63903.1
YgjD/Kae1/Qri7 family, required for N6-threonylcarbamoyl adenosine t(6)A37 modification in tRNA; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belo [...]
    
 
 0.825
AKB65728.1
Hypothetical protein.
 
     0.718
AKB65510.1
Hypothetical protein.
  
     0.697
AKB66458.1
Archaeosortase A.
  
     0.697
AKB64051.1
Hypothetical protein.
  
     0.689
AKB63858.1
Oligosaccharyl transferase.
  
     0.684
AKB65913.1
Hypothetical protein.
  
     0.680
AKB63917.1
Hypothetical protein.
 
     0.679
AKB63859.1
Oligosaccharyl transferase.
  
     0.677
AKB65191.1
ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase.
  
     0.677
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.